Multilevel Interactions of Stress and Circadian System: Implications for Traumatic Stress
نویسندگان
چکیده
منابع مشابه
Chronic stress and plasticity in the limbic system: Implications for post traumatic stress disorder
i ABSTRACT The brain is a fundamental target of the stress response that promotes adaptation and survival but the repeated activation of the stress response has the potential alter cognition, emotion, and motivation, key functions of the limbic system. Three structures of the limbic system in particular, the hippocampus, medial prefrontal cortex (mPFC), and amygdala, are of special interest due...
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Many physiological processes fluctuate throughout the day/night and daily fluctuations are observed in brain and peripheral levels of several hormones, neuropeptides and transmitters. In turn, mediators under the "control" of the "master biological clock" reciprocally influence its function. Dysregulation in the rhythmicity of hormone release as well as hormone receptor sensitivity and availabi...
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Post-traumatic stress disorder (PTSD) is a common consequence of exposure to a life-threatening event. Currently, pharmacological treatments are limited by high rates of relapse, and novel treatment approaches are needed. We have recently demonstrated that propranolol, a β-adrenergic antagonist, inhibited aversive memory reconsolidation in animals. Following this, in an open-label study 70% of ...
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ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2020
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2019.01003